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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NTRK2
All Species:
18.48
Human Site:
T151
Identified Species:
45.19
UniProt:
Q16620
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16620
NP_001007098.1
822
91999
T151
I
L
V
G
N
P
F
T
C
S
C
D
I
M
W
Chimpanzee
Pan troglodytes
Q5IS37
825
92786
Q145
R
L
T
T
L
S
W
Q
L
F
Q
T
L
S
L
Rhesus Macaque
Macaca mulatta
XP_001107330
822
91946
T151
I
L
V
G
N
P
F
T
C
S
C
D
I
M
W
Dog
Lupus familis
XP_848589
838
93718
T151
I
L
V
G
N
P
F
T
C
S
C
D
I
M
W
Cat
Felis silvestris
Mouse
Mus musculus
P15209
821
92115
T151
I
L
T
G
N
P
F
T
C
S
C
D
I
M
W
Rat
Rattus norvegicus
Q63604
821
92168
T151
I
L
T
G
N
P
F
T
C
S
C
D
I
M
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q91987
818
91718
K150
I
L
V
D
N
P
F
K
C
S
C
E
I
M
W
Frog
Xenopus laevis
O73798
1358
153845
I402
F
L
K
S
L
R
Y
I
L
G
E
E
Q
M
P
Zebra Danio
Brachydanio rerio
XP_001919963
922
103561
Q268
L
L
S
G
N
P
L
Q
C
A
C
E
N
I
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24488
685
78124
S61
S
N
A
H
V
F
V
S
P
N
L
T
M
N
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.8
99.8
96.4
N.A.
93.9
93.5
N.A.
N.A.
77.6
22.3
55.5
N.A.
27.4
N.A.
N.A.
N.A.
Protein Similarity:
100
70.6
99.8
97.1
N.A.
97.1
96.5
N.A.
N.A.
86.5
35.5
66.1
N.A.
45
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
93.3
93.3
N.A.
N.A.
80
13.3
46.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
93.3
93.3
N.A.
N.A.
86.6
26.6
73.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
70
0
70
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
50
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
30
0
0
0
% E
% Phe:
10
0
0
0
0
10
60
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
60
0
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
60
0
0
0
0
0
0
10
0
0
0
0
60
10
0
% I
% Lys:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
10
90
0
0
20
0
10
0
20
0
10
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
70
0
% M
% Asn:
0
10
0
0
70
0
0
0
0
10
0
0
10
10
0
% N
% Pro:
0
0
0
0
0
70
0
0
10
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
20
0
0
10
0
10
0
0
% Q
% Arg:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
10
10
0
10
0
10
0
60
0
0
0
10
0
% S
% Thr:
0
0
30
10
0
0
0
50
0
0
0
20
0
0
0
% T
% Val:
0
0
40
0
10
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
70
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _